Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978127 | 1.00 | TRPV4 (0.35) | TRPV4ALDH1A1GAATDP1CCND3 | |
| SCHEMBL30309547 | 0.89 | TRPV4 (0.38) | TRPV4ALDH1A1GAATDP1CCND3 | |
| SCHEMBL30309538 | 0.89 | AURKA (0.38) | ALDH1A1GAANPC1RAB9AKMT2A | |
| SCHEMBL23978109 | 0.89 | AURKA (0.38) | ALDH1A1GAANPC1RAB9AKMT2A | |
| SCHEMBL23978116 | 0.89 | TRPV4 (0.38) | TRPV4ALDH1A1GAATDP1CCND3 | |
| SCHEMBL23978385 | 0.87 | TRPV4 (0.34) | TRPV4ALDH1A1GAATDP1CCND3 | |
| SCHEMBL30309543 | 0.87 | TRPV4 (0.34) | TRPV4ALDH1A1GAATDP1CCND3 | |
| SCHEMBL23978096 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL30309515 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23978367 | 0.78 | MAPK1 (0.32) | NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143191-A2 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | iOmx Therapeutics AG (DE) | 2023-03-08 | — | — | EP | disclosed |