Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574919 | 0.77 | GAA (0.44) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL27692333 | 0.77 | TET2 (0.39) | EGLN1ALDH1A1 | |
| SCHEMBL3907402 | 0.74 | GAA (0.41) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL13552393 | 0.73 | EGLN1 (0.63) | EGLN1ALDH1A1GAAMGAMSI | |
| SCHEMBL22876787 | 0.72 | FAAH (0.41) | EGLN1ALDH1A1 | |
| SCHEMBL7225123 | 0.72 | — | — | |
| SCHEMBL259628 | 0.72 | — | — | |
| SCHEMBL23002422 | 0.71 | KMT2A (0.54) | ALDH1A1GAASMN1; SMN2HTTKDM4E | |
| SCHEMBL1101451 | 0.71 | POLB (0.38) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL9150632 | 0.71 | GAA (0.50) | EGLN1ALDH1A1PKMGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204494-B | Oxygen-substituted phenylimidazole XOR/URAT1 dual inhibitor and preparation and application thereof | 华南理工大学 | 2023-03-24 | — | — | CN | disclosed |