Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355253 | 0.85 | GAA (0.55) | GAASMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL3135183 | 0.82 | GAA (0.50) | GAASMN1; SMN2HTTEGLN1ALDH1A1 | |
| SCHEMBL29201470 | 0.82 | EGLN1 (0.55) | GAASMN1; SMN2HTTEGLN1ALDH1A1 | |
| SCHEMBL19255014 | 0.80 | GAA (0.50) | GAASMN1; SMN2HTTEGLN1ALDH1A1 | |
| SCHEMBL26007510 | 0.80 | GAA (0.49) | GAASMN1; SMN2HTTEGLN1ALDH1A1 | |
| SCHEMBL10818731 | 0.80 | ALOX15 (0.46) | GAASMN1; SMN2EGLN1ALDH1A1KDM4E | |
| SCHEMBL9150625 | 0.80 | SMN1; SMN2 (0.47) | GAASMN1; SMN2EGLN1ALDH1A1TDP1 | |
| SCHEMBL23988162 | 0.79 | EGLN1 (0.52) | GAASMN1; SMN2HTTEGLN1ALDH1A1 | |
| SCHEMBL8344696 | 0.78 | GAA (0.47) | GAASMN1; SMN2HTTEGLN1ALDH1A1 | |
| SCHEMBL10893317 | 0.78 | GAA (0.47) | GAASMN1; SMN2HTTEGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397821-A | Light and heat stabilizers, low volatility | ELFATOCHEM NORTH AMERICA, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-5338853-A | N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0434080-A1 | Derivatives of N-hals-substituted amic acid hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |