Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035562 | 1.00 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL316529 | 1.00 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL17923480 | 0.82 | MEN1 (0.46) | ACACBACACA | |
| SCHEMBL13983797 | 0.79 | ACACB (0.42) | ACACBACACA | |
| SCHEMBL540666 | 0.79 | ACACB (0.65) | ACACBACACA | |
| SCHEMBL1754100 | 0.79 | ACACB (0.65) | ACACBACACA | |
| SCHEMBL13778592 | 0.79 | ACACB (0.56) | ACACBACACA | |
| SCHEMBL640385 | 0.79 | ACACB (0.65) | ACACBACACA | |
| SCHEMBL27555544 | 0.78 | CYP1A2 (0.40) | ACACBACACA | |
| SCHEMBL6966307 | 0.78 | ACACB (0.54) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216791-A1 | PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | ASTRAZENECA (SE) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216791-A1 | PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | BRAF, RAF1, ARAF | ACACB 3667/4885ACACA 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.