SCHEMBL540666

SCHEMBL540666

CC(=O)NC(C)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.65
ACACA Q13085 4/20 0.65
HSD17B10 Q99714 2/20 0.61
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
ALDH1A1 P00352 3/20 0.58
KDM4E B2RXH2 2/20 0.58
LMNA P02545 2/20 0.58
HPGD P15428 1/20 0.58
HDAC6 Q9UBN7 1/20 0.57
TDP1 Q9NUW8 1/20 0.56
POLB P06746 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
RECQL P46063 1/20 0.56
MAPT P10636 1/20 0.56
NPC1 O15118 1/20 0.56
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1754100 1.00 ACACB (0.65) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL640385 1.00 ACACB (0.65) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL5043127 0.98 ACACB (0.63) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL3861309 0.91 ACACB (0.56) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL7736414 0.88 ACACB (0.77) ACACBACACAMEN1KMT2AALDH1A1
SCHEMBL25336459 0.84 MMP9 (0.66) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL247742 0.84 HSD17B10 (0.63) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL8715641 0.84 HSD17B10 (0.75) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL249524 0.84 HSD17B10 (0.63) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL2672977 0.84 HSD17B10 (0.63) HSD17B10MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110403931-B Medical application of 5-hydroxyflavone substituted N-phenethyl acetamide in resisting mycobacterium tuberculosis infection 厦门大学 2022-08-23 CN claimed
CN-108299251-B Preparation method of glimepiride impurity 山东新华制药股份有限公司 2020-10-30 CN claimed
CN-110403930-A Medical usage of 5- Sunkatol No. 1 substitution-N-3 ' the methylbenzyl acetamide in Killing Mycobacterium Tuberculosis infection UNIV XIAMEN 2019-11-05 CN claimed
CN-107567445-A It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor 坎塞拉有限公司 2018-01-09 CN claimed
CN-104152525-B A kind of method that fractionation prepares the phenyl ethylamines of optical voidness R 1 上海同昌生物医药科技有限公司 2017-09-29 CN claimed
CN-104152526-B The method of optical voidness R-1-phenethylamine is prepared in a kind of fractionation 六安佳诺生化科技有限公司 2016-12-07 CN claimed
CN-104131062-B The method of optical voidness S-1-phenethylamine is prepared in a kind of fractionation 陈永军 2016-11-23 CN claimed
CN-104151169-B The method of optical voidness S-1-phenethylamine is prepared in a kind of fractionation 六安佳诺生化科技有限公司 2016-08-24 CN claimed
CN-104152525-A Resolution method for preparing optically pure R-1-phenylethylamine CHEN YONGJUN 2014-11-19 CN claimed
CN-104151169-A Method for resolution preparation of optically pure S-1-phenylethylamine CHEN YONGJUN 2014-11-19 CN claimed
WO-1997041214-A1 BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY NOVARTIS AG (CH) 1997-11-06 WO claimed
EP-0594608-B1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RES CORP TECHNOLOGIES INC (US) 1997-10-15 EP claimed
EP-0594608-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1994-05-04 EP claimed
US-5296595-A Metal complexes with bridging ligands RESEARCH CORPORATION TECHNOLOGIES (US) 1994-03-22 US claimed
EP-0594608-A4 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1993-03-15 EP claimed
EP-0459983-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES PHARMACIA & UPJOHN COMPANY (US) 1991-12-11 EP claimed
WO-1991014672-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-03 WO claimed
EP-0201039-B1 L-AMINOACYLASES BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-07-31 EP claimed
WO-1990006921-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES THE UPJOHN COMPANY (US) 1990-06-28 WO claimed
EP-0201039-A2 L-aminoacylases BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-11-12 EP claimed