SCHEMBL640385

SCHEMBL640385

CC(=O)N[C@@H](C)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.65
ACACA Q13085 4/20 0.65
HSD17B10 Q99714 2/20 0.61
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
ALDH1A1 P00352 3/20 0.58
KDM4E B2RXH2 2/20 0.58
LMNA P02545 2/20 0.58
HPGD P15428 1/20 0.58
HDAC6 Q9UBN7 1/20 0.57
TDP1 Q9NUW8 1/20 0.56
POLB P06746 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
RECQL P46063 1/20 0.56
MAPT P10636 1/20 0.56
NPC1 O15118 1/20 0.56
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1754100 1.00 ACACB (0.65) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL540666 1.00 ACACB (0.65) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL5043127 0.98 ACACB (0.63) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL3861309 0.91 ACACB (0.56) ACACBACACAHSD17B10MEN1KMT2A
SCHEMBL7736414 0.88 ACACB (0.77) ACACBACACAMEN1KMT2AALDH1A1
SCHEMBL25336459 0.84 MMP9 (0.66) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL247742 0.84 HSD17B10 (0.63) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL8715641 0.84 HSD17B10 (0.75) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL249524 0.84 HSD17B10 (0.63) HSD17B10MEN1KMT2AALDH1A1KDM4E
SCHEMBL2672977 0.84 HSD17B10 (0.63) HSD17B10MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9241222-A None JP disclosed
WO-2025119351-A1 GPR139 AGONIST 深圳湾实验室 2025-06-12 WO disclosed
US-20250185669-A1 ANTI-VIRAL PAINTS AND COATINGS AND ARTICLES COMPRISING SAME Reactive Surfaces Ltd., LLP (US) 2025-06-12 US disclosed
US-12232498-B2 Anti-viral paints and coatings and articles comprising same Reactive Surfaces Ltd., LLP (US) 2025-02-25 US disclosed
US-12110302-B2 Metal complex, intermediate, and preparation method and application thereof SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2024-10-08 US disclosed
EP-3865494-B1 METAL COMPLEX, INTERMEDIATE, AND PREPARATION METHOD AND APPLICATION THEREOF SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) 2024-07-24 EP disclosed
US-20240172762-A1 ANTI-VIRAL PAINTS AND COATINGS AND ARTICLES COMPRISING SAME Reactive Surfaces Ltd., LLP (US) 2024-05-30 US disclosed
US-11980192-B2 Anti-viral paints and coatings and articles comprising same Reactive Surfaces Ltd., LLP (US) 2024-05-14 US disclosed
US-20240016160-A1 ANTI-VIRAL PAINTS AND COATINGS AND ARTICLES COMPRISING SAME Reactive Surfaces Ltd., LLP (US) 2024-01-18 US disclosed
US-11832617-B2 Anti-viral paints and coatings and articles comprising same Reactive Surfaces Ltd., LLP (US) 2023-12-05 US disclosed
US-20030018034-A1 Piperazine compounds and medicinal use thereof MITSUBISHI PHARMA CORPORATION 2003-01-23 US disclosed
US-6455528-B1 TUMOR NECROSIS FACTOR ANTAGONIST AND/OR INTERLEUKIN PROMOTER; ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE TREATMENT MITSUBISHI PHARMA CORPORATION (JP) 2002-09-24 US disclosed
US-6235516-B1 FROM RHODOCOCCUS GLOBERULUS, RHODOCOCCUS EQUI OR ARTHROBACTER AURESCENS NOVARTIS AG (CH) 2001-05-22 US disclosed
EP-1029851-A1 PIPERAZINE COMPOUNDS AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2000-08-23 EP disclosed
EP-0954571-A1 BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY Novartis AG (CH) 1999-11-10 EP disclosed
US-5952527-A A COMPLEX OF TRANSITIONAL METAL COMPOUND, CYCLOOCTADIENE OR CYCLOPENTADIENE AND 2,2-BIS/DIPHENYLPHOSPHINOAMINO/-5,5',6,6'7,7',8,8'-OCTAHYDRO-1 ,1'-BINAPHTHYL COMPOUND; USED AS HYDROGENATION CATALYST THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 1999-09-14 US disclosed
US-5919981-A USING HYDROGENATION 1,1*-BINAPHTHYL-2,2*-DIAMINE AS CHEMICAL INTERMEDIATE THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 1999-07-06 US disclosed
WO-1997041214-A1 BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY NOVARTIS AG (CH) 1997-11-06 WO disclosed
JP-H09241222-A PRODUCTION OF AMINE SAGAMI CHEM RES CENTER 1997-09-16 JP disclosed
EP-0399589-A1 Preparation of N-acyl alkylamines SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12110302-B2 Metal complex, intermediate, and preparation method and application thereof AP2M1, AP3M1, AP1M1 ACACB 1337/4885ACACA 775/4885HSD17B10 1478/4885
US-20030018034-A1 Piperazine compounds and medicinal use thereof TNF, IL5, CCR10 ACACB 1289/4885ACACA 1336/4885HSD17B10 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.