Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 2/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29063147 | 1.00 | CTSL (0.39) | CTSLCTSBNOD1GRNSORT1 | |
| SCHEMBL23824535 | 0.93 | CTSL (0.44) | CTSLCTSB | |
| SCHEMBL29063282 | 0.93 | CTSL (0.44) | CTSLCTSB | |
| SCHEMBL23824532 | 0.93 | CTSL (0.44) | CTSLCTSB | |
| SCHEMBL23824408 | 0.91 | MMP1 (0.36) | CTSLCTSB | |
| SCHEMBL23824709 | 0.91 | MMP1 (0.36) | CTSLCTSB | |
| SCHEMBL23824665 | 0.91 | CTSL (0.47) | CTSLCTSBGRNSORT1LTA4H | |
| SCHEMBL23824410 | 0.91 | MMP1 (0.36) | CTSLCTSB | |
| SCHEMBL23824663 | 0.91 | CTSL (0.47) | CTSLCTSBGRNSORT1LTA4H | |
| SCHEMBL30310593 | 0.91 | MMP1 (0.36) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |