Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113156 | 1.00 | GPR84 (0.52) | GPR84TACR1NR3C1NR3C2ADRB3 | |
| SCHEMBL1196810 | 1.00 | GPR84 (0.52) | GPR84TACR1NR3C1NR3C2ADRB3 | |
| SCHEMBL25244600 | 0.86 | NR4A2 (0.53) | GPR84TACR1MAPTMEN1KMT2A | |
| SCHEMBL25288578 | 0.86 | NR4A2 (0.53) | GPR84TACR1MAPTMEN1KMT2A | |
| SCHEMBL2013301 | 0.86 | MTNR1A (0.58) | TACR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL24113154 | 0.85 | GPR84 (0.56) | GPR84TACR1NR3C1NR3C2ADRB3 | |
| SCHEMBL109837 | 0.85 | KMT2A (0.62) | GPR84TACR1NR3C1NR3C2ADRB3 | |
| SCHEMBL21055747 | 0.85 | KMT2A (0.62) | GPR84TACR1NR3C1NR3C2ADRB3 | |
| SCHEMBL18028997 | 0.85 | KMT2A (0.62) | GPR84TACR1NR3C1NR3C2ADRB3 | |
| SCHEMBL16975866 | 0.85 | GPR84 (0.56) | GPR84TACR1NR3C1NR3C2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |