⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302707 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL9219931 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL577753 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL2564589 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL3386412 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL2565171 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL304992 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL577732 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL59455 | 1.00 | — | — | |
| SCHEMBL303552 | 1.00 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| WO-2024135828-A1 | AVERMECTIN DERIVATIVE | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2024-06-27 | — | — | WO | disclosed |
| US-20230337672-A1 | METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230232827-A1 | METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-27 | — | — | US | disclosed |
| WO-2022004702-A1 | METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE | 住友化学株式会社 | 2022-01-06 | — | — | WO | disclosed |
| WO-2022004704-A1 | METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES | 住友化学株式会社 | 2022-01-06 | — | — | WO | disclosed |
| WO-2020255895-A1 | OIL-IN-WATER SILICONE EMULSION COMPOSITION AND USE THEREOF | ダウ・東レ株式会社 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020255894-A1 | AQUEOUS COATING-FILM-FORMING COMPOSITION FOR FORMING LUBRICATING COATING FILM, AND AIR BAG USING SAID COMPOSITION | ダウ・東レ株式会社 | 2020-12-24 | — | — | WO | disclosed |
| EP-2924044-B1 | PLATINUM COMPOUND OF MALONIC ACID DERIVATIVE HAVING LEAVING GROUP CONTAINING AMINO OR ALKYLAMINO | BEIJING SHUOBAI PHARMACEUTICAL CO LTD (CN) | 2018-10-31 | — | — | EP | disclosed |
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | disclosed |
| WO-1997037665-A1 | METHOD OF TREATING HEART FAILURE WITH ENDOTHELIN ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-10-16 | — | — | WO | disclosed |
| EP-0761658-A1 | Azole-phenyl urea derivatives as ACAT inhibitors and their production | NIHON NOHYAKU CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| US-5561142-A | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity | MERCK & CO., INC. (US) | 1996-10-01 | — | — | US | disclosed |
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |
| WO-1996011196-A1 | PYRAZOLYLMETHYL-THIAZOLIDINES USEFUL AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-4721779-A | ELECTROOPTICAL APPARATUS | BASF AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |
| US-4665087-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0034743-A1 | Benzoxazoles, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-09-02 | — | — | EP | disclosed |