Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302707 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL303118 | 1.00 | — | — | |
| SCHEMBL9219931 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL2564589 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL3386412 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL2565171 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL304992 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL577732 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL59455 | 1.00 | — | — | |
| SCHEMBL303552 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042007-B1 | AMINOBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS | ALCON LAB INC (US) | 2004-08-11 | — | — | EP | claimed |
| EP-1640361-B9 | ASYMMETRIC UREA COMPOUNDS AND PROCESS FOR PRODUCING ASYMMETRIC COMPOUNDS BY ASYMMETRIC CONJUGATE ADDITION REACTION USING THE SAME AS CATALYST | SUMITOMO CHEMICAL CO (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-9073823-B2 | Compound having hetero ring skeleton, and process for producing optically active compound using the aforementioned compound as asymmetric catalyst | KYOTO UNIVERSITY (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-1640361-B1 | ASYMMETRIC UREA COMPOUNDS AND PROCESS FOR PRODUCING ASYMMETRIC COMPOUNDS BY ASYMMETRIC CONJUGATE ADDITION REACTION USING THE SAME AS CATALYST | SUMITOMO CHEMICAL CO (JP) | 2015-05-27 | — | — | EP | disclosed |
| CN-102459194-B | Compound having hetero ring skeleton, and process for producing optically active compound using the aforementioned compound as asymmetric catalyst | KYOTO UNIVERSITY (JP) | 2014-10-29 | — | — | CN | disclosed |
| US-8580804-B2 | Compound having hetero ring skeleton, and process for producing optically active compound using the aforementioned compound as asymmetric catalyst | KYOTO UNIVERSITY (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20130245257-A1 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-19 | — | — | US | disclosed |
| EP-2418204-B1 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST | UNIV KYOTO (JP) | 2013-07-24 | — | — | EP | disclosed |
| CN-102459194-A | Compound having heterocyclic skeleton and method for producing optically active compound using the same as asymmetric catalyst | UNIV KYOTO | 2012-05-16 | — | — | CN | disclosed |
| US-20120095227-A1 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-19 | — | — | US | disclosed |
| US-4133686-A | ANILINOPYRAZOLINONE MAGENTA COLOR FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1979-01-09 | — | — | US | disclosed |
| US-4105649-A | AQUEOUS POLYMERIC THICKENING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
| US-4038265-A | VINYL BENZYL ETHERS AND NONIONIC WATER SOLUBLE THICKENING AGENTS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4029874-A | Vinyl benzyl ethers and nonionic water soluble thickening agents prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4029872-A | Vinyl benzyl ethers and nonionic water soluble thickening agents prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4008202-A | Aqueous thickening agents derived from vinyl benzyl ether polymers | THE DOW CHEMICAL COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3963684-A | COPOLYMERS WITH ACRYLAMIDE | THE DOW CHEMICAL COMPANY (US) | 1976-06-15 | — | — | US | disclosed |
| US-3960570-A | ALPHA-ACYLACETOAMIDE YELLOW DYE FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | disclosed |
| US-3951591-A | Process for dyeing synthetic fiber materials | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3935016-A | Silver halide color photographic materials containing 3-anilino-5-pyrazolone couplers | FUJI PHOTO FILM COMPANY, LTD. (JA) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245257-A1 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST | COASY, LSS, INF2 | TSHR 4515/4885THRB 3553/4885MEN1 309/4885 |
| US-20120095227-A1 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST | CCNL2, ASH2L, AHR | TSHR 2501/4885THRB 1410/4885MEN1 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.