Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302707 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL303118 | 1.00 | — | — | |
| SCHEMBL9219931 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL577753 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL3386412 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL2565171 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL304992 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL577732 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL59455 | 1.00 | — | — | |
| SCHEMBL303552 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554340-A2 | CHARGE DISSIPATION MODIFIERS FOR OLEFINIC INTERPOLYMER COMPOSITIONS | DUPONT DOW ELASTOMERS L.L.C. (US) | 2005-07-20 | — | — | EP | claimed |
| WO-2004037909-A2 | CHARGE DISSIPATION MODIFIERS FOR OLEFINIC INTERPOLYMER COMPOSITIONS | DUPONT DOW ELASTOMERS L.L.C. (US) | 2004-05-06 | — | — | WO | claimed |
| US-4576708-A | HYDROGENATION, LIQUEFACTION | CITIES SERVICE OIL & GAS CORP. (US) | 1986-03-18 | — | — | US | claimed |
| US-8729115-B2 | Valsartan derivatives carrying nitrogen oxide donors for the treatment of vascular and metabolic diseases | CARDIOLYNX AG (CH) | 2014-05-20 | — | — | US | disclosed |
| US-8703800-B2 | Nitrate and diazeniumdiolate derivatives of pioglitazone | CARDIOLYNX AG (CH) | 2014-04-22 | — | — | US | disclosed |
| EP-2576545-A1 | NITRATE AND DIAZENIUMDIOLATE DERIVATIVES OF PIOGLITAZONE | Cardiolynx AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| US-20130072525-A1 | NITRATE AND DIAZENIUMDIOLATE DERIVATIVES OF PIOGLITAZONE | CARDIOLYNX AG (CH) | 2013-03-21 | — | — | US | disclosed |
| US-20130041001-A1 | VALSARTAN DERIVATIVES CARRYING NITROGEN OXIDE DONORS FOR THE TREATMENT OF VASCULAR AND METABOLIC DISEASES | CARDIOLYNX AG (CH) | 2013-02-14 | — | — | US | disclosed |
| WO-2011151362-A1 | NITRATE AND DIAZENIUMDIOLATE DERIVATIVES OF PIOGLITAZONE | CARDIOLYNX AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011131613-A1 | VALSARTAN DERIVATIVES CARRYING NITROGEN OXIDE DONORS FOR THE TREATMENT OF VASCULAR AND METABOLIC DISEASES | CARDIOLYNX AG (CH) | 2011-10-27 | — | — | WO | disclosed |
| EP-1904556-A2 | POLYASPARTIC ACID DERIVATIVES IN COVERING AGENTS CONTAINING POLYSILOXANE | Lanxess Deutschland GmbH (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-0334362-A2 | Heat developable color light-sensitive material | Fuji Photo Film Co., Ltd. (JP) | 1989-09-27 | — | — | EP | disclosed |
| EP-0306833-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |
| US-4783396-A | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| US-H533-H | 1H-PYRAZOLO(1,5-B)OR(5,1-C)-1,2,4-TRIAZOLE MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0280252-A2 | Silver halide photographic material and method for forming super high contrast image therewith | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-31 | — | — | EP | disclosed |
| EP-0220746-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |
| US-4286085-A | PROMOTERS INTERFACIAL POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 1981-08-25 | — | — | US | disclosed |
| US-4145219-A | HIGH SPEED SILVER HALIDE EMULSION CONTAINING DEVELOPMENT INHIBITOR RELEASING (DIR) COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-3944670-A | Pesticidal dithiazolium salts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041001-A1 | VALSARTAN DERIVATIVES CARRYING NITROGEN OXIDE DONORS FOR THE TREATMENT OF VASCULAR AND METABOLIC DISEASES | GLS, REN, NAT1 | TSHR 2781/4885THRB 1661/4885MEN1 1075/4885 |
| US-20130072525-A1 | NITRATE AND DIAZENIUMDIOLATE DERIVATIVES OF PIOGLITAZONE | PPARD, NOS2, PPARA | TSHR 2177/4885THRB 2083/4885MEN1 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.