Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24171246 | 1.00 | BRD4 (0.40) | BRD4ALDH1A1VCPWEE1EGFR | |
| SCHEMBL24172531 | 0.93 | EGFR (0.43) | ALDH1A1VCPWEE1EGFREML4 | |
| SCHEMBL21311084 | 0.82 | EGFR (0.50) | ALDH1A1EGFRKDM4ENTRK1CSF1R | |
| SCHEMBL28693282 | 0.77 | ALDH1A1 (0.39) | ALDH1A1VCPWEE1EGFREML4 | |
| SCHEMBL6419563 | 0.75 | TERT (0.43) | ALDH1A1EGFRNTRK1CSF1RNTRK2 | |
| SCHEMBL30377459 | 0.75 | EGFR (0.52) | ALDH1A1EGFRKDM4E | |
| SCHEMBL21310875 | 0.74 | TERT (0.44) | ALDH1A1EGFRNTRK1CSF1RNTRK2 | |
| SCHEMBL24172536 | 0.72 | ALDH1A1 (0.41) | ALDH1A1VCPEGFREML4ALK | |
| SCHEMBL21311035 | 0.72 | EGFR (0.52) | EGFR | |
| SCHEMBL24171299 | 0.72 | ALDH1A1 (0.41) | ALDH1A1VCPWEE1EGFREML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867542-B | Novel benzimidazole compound | 微境生物医药科技(上海)有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-115867542-A | Novel benzimidazole compounds | 微境生物医药科技(上海)有限公司 | 2023-03-28 | — | — | CN | disclosed |