Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HK1 | P19367 | 1/20 | 0.63 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305059 | 1.00 | ALDH1A1 (0.63) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL1399840 | 0.89 | ALDH1A1 (0.76) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL12305133 | 0.85 | ALDH1A1 (0.58) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL130198 | 0.83 | ALDH1A1 (0.69) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| Bromide SCHEMBL3252601 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| Bromide SCHEMBL6958062 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL31173192 | 0.81 | ALDH1A1 (0.56) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL22290461 | 0.81 | ALDH1A1 (0.56) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL4636395 | 0.80 | TSHR (0.72) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL22290627 | 0.80 | ALDH1A1 (0.59) | ALDH1A1RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917527-B1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-113645971-B | Compounds and uses thereof | 福宏治疗公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-115867314-A | Methods of treating cancer | 福宏治疗公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20230079819-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079819-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | ALDH1A1 2571/4885RAB9A 572/4885MAPT 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.