Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.53 |
| ▸ | ACE | P12821 | 11/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29290367 | 0.88 | ACE (0.53) | LTA4HACEACE2 | |
| SCHEMBL7087531 | 0.81 | ACE (0.56) | LTA4HACEACE2 | |
| SCHEMBL29290359 | 0.81 | ACE (0.56) | LTA4HACEACE2 | |
| SCHEMBL27890165 | 0.79 | ACE (0.73) | LTA4HACEACE2 | |
| SCHEMBL27890164 | 0.79 | ACE (0.73) | LTA4HACEACE2 | |
| Trifluoroacetic Acid SCHEMBL3700603 | 0.79 | ACE (0.64) | LTA4HACE | |
| SCHEMBL12253518 | 0.78 | ACE (0.52) | LTA4HACEACE2 | |
| SCHEMBL11558098 | 0.77 | LTA4H (0.75) | LTA4HACEACE2 | |
| SCHEMBL11258916 | 0.77 | ACE (0.75) | LTA4HACE | |
| SCHEMBL30785955 | 0.77 | ACE (0.56) | LTA4HACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4412656-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | Vincerx Pharma GmbH (DE) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023057814-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |