Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 15/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 13/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.50 |
| ▸ | CDK2 | P24941 | 14/20 | 0.49 |
| ▸ | CDK9 | P50750 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 10/20 | 0.45 |
| ▸ | CDK7 | P50613 | 10/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.45 |
| ▸ | CCNH | P51946 | 9/20 | 0.45 |
| ▸ | CCND1 | P24385 | 8/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.45 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312865 | 1.00 | CDK1 (0.50) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL30315332 | 0.83 | CDK5 (0.53) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2310970 | 0.83 | CDK5 (0.53) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL21017207 | 0.82 | CDK2 (0.52) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2315371 | 0.81 | CDK2 (0.54) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL25308297 | 0.78 | CCNK (0.64) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL30518535 | 0.78 | CCNK (0.64) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2318356 | 0.77 | AHR (0.51) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL30518560 | 0.77 | CDK2 (0.56) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL25309378 | 0.77 | CDK2 (0.56) | CDK1CCNB1CDK5CDK5R1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-B1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | NOVARTIS AG (CH) | 2023-03-29 | — | — | EP | disclosed |