Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532254 | 1.00 | GAA (0.37) | GAATHRBHSD17B10HPGDTSHR | |
| Hydrochloric Acid SCHEMBL8075443 | 0.98 | GAA (0.36) | GAATHRBHSD17B10HPGDTSHR | |
| SCHEMBL8083612 | 0.85 | GAA (0.34) | GAATHRBHSD17B10HPGDTSHR | |
| Hydrochloric Acid SCHEMBL8075471 | 0.83 | GAA (0.33) | GAATHRBHSD17B10HPGDTSHR | |
| SCHEMBL8088989 | 0.82 | HPGD (0.42) | GAAHSD17B10HPGDLMNAMAPT | |
| SCHEMBL7761763 | 0.81 | CYP1A2 (0.41) | GAAHSD17B10TSHRALOX15CYP3A4 | |
| Hydrochloric Acid SCHEMBL8088632 | 0.80 | HPGD (0.41) | GAAHSD17B10HPGDLMNAMAPT | |
| SCHEMBL12774727 | 0.78 | SIRT1 (0.47) | GAATHRBHSD17B10HPGDTSHR | |
| SCHEMBL9538794 | 0.76 | HPGD (0.33) | GAATHRBHSD17B10HPGDTSHR | |
| SCHEMBL5526674 | 0.75 | THRB (0.46) | GAATHRBHSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9100417-A | — | — | None | — | — | JP | disclosed |
| US-9522906-B2 | Tetrahydroquinoline analogues as muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20140221364-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8680115-B2 | Tetrahydroquinoline analogues as muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20100216840-A1 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20090239903-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-7576078-B2 | Tetrahydroquinoline analogues as muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576100-B2 | Muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7550459-B2 | Neurodegenerative diseases, psychological disorders; e.g. 4-[3-(3a -Cyclopropylmethoxy-8-azabicyclo[3.2.1]oct-8-yl)-2-methylpropyl]-4H-benzo[1.4]oxazin-3-one | ACADIA PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080070948-A1 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2008-03-20 | — | — | US | disclosed |
| EP-0250954-A2 | Colour-photographic recording material with a dye releaser for blue-green dyes, and a colour picture produced with these dyes | Agfa-Gevaert AG (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0243100-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0243096-A2 | Method for processing a light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-10-28 | — | — | EP | disclosed |
| US-4686177-A | CYAN COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| US-4670608-A | CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| US-4623616-A | DIFFUSIONPROOF COUPLER, TRIAZINE HARDENING AGENT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-11-18 | — | — | US | disclosed |
| EP-0175151-A1 | 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation | BAYER AG (DE) | 1986-03-26 | — | — | EP | disclosed |
| US-4564590-A | Silver halide photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0157363-A2 | Silver halide photografic material | KONICA CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |
| EP-0156377-A1 | Silver halide photographic material | KONICA CORPORATION (JP) | 1985-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070948-A1 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | CHRM4, CHRM1, CHRM2 | GAA 3236/4885THRB 203/4885HSD17B10 4564/4885 |
| US-20140221364-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | CHRM3, CHRM5, CHRM2 | GAA 1783/4885THRB 237/4885HSD17B10 1962/4885 |
| US-20090239903-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | CHRM3, CHRM5, CHRM2 | GAA 1783/4885THRB 237/4885HSD17B10 1962/4885 |
| US-20100216840-A1 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | CHRM4, CHRM1, CHRM2 | GAA 3236/4885THRB 203/4885HSD17B10 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.