SCHEMBL30316596

SCHEMBL30316596

Cln1ncc2nccnc21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BMP4 P12644 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25200588 1.00 BMP4 (0.31) BMP4ELANE
SCHEMBL19269980 0.67 PIK3CD (0.37)
SCHEMBL12844448 0.67 XDH (0.41)
SCHEMBL23227964 0.67 KDM4E (0.55)
SCHEMBL29892154 0.66 ELANE (0.38) ELANE
SCHEMBL11082703 0.64 KDM4E (0.61)
SCHEMBL19274936 0.64
SCHEMBL30015162 0.64 ELANE (0.37) ELANE
SCHEMBL31507588 0.64 KDM4E (0.31) BMP4
SCHEMBL25154463 0.63 GRIN2B (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363423-A1 CDK2 INHIBITORS Blueprint Medicines Corporation (US) 2024-05-08 EP disclosed
WO-2023278326-A1 CDK2 INHIBITORS BLUEPRINT MEDICINES CORPORATION (US) 2023-01-05 WO disclosed