Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 16/20 | 1.00 |
| ▸ | CSNK2B | P67870 | 16/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 16/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046992 | 0.88 | CSNK2A2 (0.79) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL24046999 | 0.86 | CSNK2A2 (0.75) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL24046755 | 0.85 | CSNK2A2 (0.73) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL24046998 | 0.84 | CSNK2A2 (0.72) | CSNK2A2CSNK2BCSNK2A1TERT | |
| SCHEMBL6613017 | 0.80 | TERT (0.88) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL24046928 | 0.79 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL24046891 | 0.79 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6617685 | 0.79 | CSNK2A2 (0.74) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL6612829 | 0.79 | TERT (0.86) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 | |
| SCHEMBL7377070 | 0.79 | CSNK2A2 (0.86) | CSNK2A2CSNK2BCSNK2A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197890-A1 | FLAVONE DERIVATIVES AND USES IN TARGETING CK2-MEDIATED DISEASES AND CONDITIONS | SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2024-06-20 | — | — | US | disclosed |
| EP-4153578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | Salk Institute for Biological Studies (US) | 2023-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197890-A1 | FLAVONE DERIVATIVES AND USES IN TARGETING CK2-MEDIATED DISEASES AND CONDITIONS | PACSIN2, CSNK1E, CSNK2A2 | CSNK2A2 3/4885CSNK2B 9/4885CSNK2A1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.