Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 18/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 18/20 | 1.00 |
| ▸ | GSK3B | P49841 | 8/20 | 1.00 |
| ▸ | GSK3A | P49840 | 7/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 6/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 3/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 1.00 |
| ▸ | AHR | P35869 | 1/20 | 0.78 |
| ▸ | AURKA | O14965 | 4/20 | 0.76 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.76 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.76 |
| ▸ | ABL1 | P00519 | 4/20 | 0.69 |
| ▸ | SRC | P12931 | 4/20 | 0.69 |
| ▸ | JAK2 | O60674 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359170 | 0.88 | CDK1 (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL29447183 | 0.88 | CDK1 (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL30597656 | 0.87 | GSK3B (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL29664066 | 0.84 | GSK3A (0.78) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL30319807 | 0.80 | GSK3A (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL30597678 | 0.76 | GSK3A (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL30319811 | 0.74 | GSK3B (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL31060593 | 0.74 | GSK3B (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL30273058 | 0.71 | GSK3A (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 | |
| SCHEMBL30319809 | 0.70 | GSK3A (1.00) | CDK1CCNB1GSK3BGSK3ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466342-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | Institut Pasteur (FR) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139242-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2023-07-27 | — | — | WO | disclosed |
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |