Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 1.00 |
| ▸ | GSK3A | P49840 | 7/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 6/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 1.00 |
| ▸ | CDK1 | P06493 | 5/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 5/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 4/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 1.00 |
| ▸ | AURKA | O14965 | 2/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 2/20 | 1.00 |
| ▸ | AURKC | Q9UQB9 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 5/20 | 0.68 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.68 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.68 |
| ▸ | CCND3 | P30281 | 3/20 | 0.68 |
| ▸ | SRC | P12931 | 2/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.68 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.67 |
| ▸ | FLT3 | P36888 | 8/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319832 | 0.87 | CDK1 (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL30319811 | 0.86 | GSK3B (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL31060593 | 0.86 | GSK3B (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL29664066 | 0.85 | GSK3A (0.78) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL30044685 | 0.79 | CDK2 (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL29726933 | 0.79 | CDK2 (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL29421607 | 0.77 | GSK3A (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL29359170 | 0.74 | CDK1 (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL29447183 | 0.74 | CDK1 (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 | |
| SCHEMBL30597678 | 0.74 | GSK3A (1.00) | GSK3BGSK3ACDK5CDK5R1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250108070-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2025-04-03 | — | — | US | claimed |
| EP-4466342-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | Institut Pasteur (FR) | 2024-11-27 | — | — | EP | claimed |
| WO-2023139242-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2023-07-27 | — | — | WO | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250108070-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2025-04-03 | — | — | US | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250108070-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | ICOS, CD4, NFATC1 | GSK3B 1583/4885GSK3A 1668/4885CDK5 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.