SCHEMBL29664066

SCHEMBL29664066

CO/N=C1\C(c2c(O)[nH]c3cc(Cl)c(Cl)cc23)=Nc2ccccc21

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3A P49840 15/20 0.78
▸ GSK3B P49841 15/20 0.78
▸ CDK5 Q00535 14/20 0.78
▸ CDK5R1 Q15078 14/20 0.78
▸ CDK1 P06493 13/20 0.78
▸ CCNB1 P14635 13/20 0.78
▸ CCNB2 O95067 12/20 0.78
▸ CCNB3 Q8WWL7 12/20 0.78
▸ AURKA O14965 2/20 0.74
▸ AURKB Q96GD4 2/20 0.74
▸ AURKC Q9UQB9 2/20 0.74
▸ AHR P35869 1/20 0.56
▸ JAK2 O60674 1/20 0.55
▸ LYN P07948 1/20 0.55
▸ HCK P08631 1/20 0.55
▸ SRC P12931 1/20 0.55
▸ JAK1 P23458 1/20 0.55
▸ CCNE1 P24864 1/20 0.55
▸ CDK2 P24941 1/20 0.55
▸ TYK2 P29597 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30597656 0.85 GSK3B (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30319832 0.84 CDK1 (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30597678 0.76 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL31060593 0.72 GSK3B (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30319811 0.72 GSK3B (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL29359170 0.72 CDK1 (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL29447183 0.72 CDK1 (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL30094663 0.67 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL29961097 0.67 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1
SCHEMBL31061457 0.65 GSK3A (1.00) GSK3AGSK3BCDK5CDK5R1CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 — — US claimed
EP-4728051-A1 STANDARDISING PLURIPOTENT STEM CELLS United Kingdom Research and Innovation (GB) 2026-04-22 — — EP claimed
US-20260015632-A1 CULTURE MEDIUM COMBINATION FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CD34+ HEMATOPOIETIC STEM/PROGENITOR CELLS SHENZHEN CELL INSPIRE BIOTECHNOLOGY CO., LTD. (CN) 2026-01-15 — — US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP claimed
US-20250268948-A1 COMPOSITIONS AND METHODS FOR TREATING POST ACUTE SEQUELAE OF SARS-COV-2 INFECTION (LONG COVID) AE CAPITAL LIMITED (VG) 2025-08-28 — — US claimed
US-20250205286-A1 COMPOSITIONS, REAGENTS, AND METHODS FOR TREATING PITT-HOPKINS SYNDROME AE CAPITAL LIMITED (VG) 2025-06-26 — — US claimed
CN-118272305-B Immune cell culture medium and application thereof 深圳泽医细胞治疗集团有限公司 2025-04-08 — — CN claimed
WO-2024256607-A1 STANDARDISING PLURIPOTENT STEM CELLS UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2024-12-19 — — WO claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO claimed
US-20240360415-A1 MUSCLE CELLS DIFFERENTIATED FROM PLURIPOTENT CELLS, METHODS OF PRODUCING SAME AND USE THEREOF ALEPH FARMS LTD. (IL) 2024-10-31 — — US claimed
CN-117802034-A Method for spontaneous assembly of pluripotent stem cells into blastocysts and application thereof 广州国家实验室 2024-04-02 — — CN claimed
CN-117795059-A Muscle cells differentiated from pluripotent cells, methods of production and uses thereof 阿利夫农场公司 2024-03-29 — — CN claimed
CN-114540278-B Microvascular in-vitro culture method and culture solution 青岛大学 2023-11-21 — — CN claimed
WO-2023200882-A1 COMPOSITIONS AND METHODS FOR TREATING POST ACUTE SEQUELAE OF SARS-COV-2 INFECTION (LONG COVID) Vitro Biopharma, Inc. (US) 2023-10-19 — — WO claimed
WO-2023183656-A1 COMPOSITIONS, REAGENTS, AND METHODS FOR TREATING PITT-HOPKINS SYNDROME Vitro Biopharma, Inc. (US) 2023-09-28 — — WO claimed
CN-115975908-A Endometrioid organ model and construction method and application thereof 北京大学第三医院(北京大学第三临床医学院) 2023-04-18 — — CN claimed
CN-114874973-B Culture medium and culture method for obtaining mature hepatocytes 深圳市三启生物技术有限公司 2023-03-21 — — CN claimed
WO-2023017509-A1 MUSCLE CELLS DIFFERENTIATED FROM PLURIPOTENT CELLS, METHODS OF PRODUCING SAME AND USE THEREOF ALEPH FARMS LTD. (IL) 2023-02-16 — — WO claimed
CN-114874973-A Culture medium and culture method for obtaining mature hepatocytes 深圳市三启生物技术有限公司 2022-08-09 — — CN claimed
CN-114540278-A Microvessel in-vitro culture method and culture solution 青岛大学 2022-05-27 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015632-A1 CULTURE MEDIUM COMBINATION FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CD34+ HEMATOPOIETIC STEM/PROGENITOR CELLS KIT, JAK1, HGF GSK3A 141/4885GSK3B 94/4885CDK5 2044/4885
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES WNT3A, GSK3B, GSK3A GSK3A 3/4885GSK3B 2/4885CDK5 919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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