Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24154769 | 1.00 | CTSK (0.42) | CTSKPDE1BPDE1APDE1CFASN | |
| SCHEMBL25305718 | 0.93 | IRAK4 (0.36) | CTSKPDE1BPDE1APDE1CFASN | |
| SCHEMBL24155296 | 0.92 | JAK2 (0.38) | CTSKPDE1BPDE1APDE1CIRAK4 | |
| SCHEMBL25307503 | 0.92 | JAK2 (0.38) | CTSKPDE1BPDE1APDE1CIRAK4 | |
| SCHEMBL24154923 | 0.92 | JAK2 (0.38) | CTSKPDE1BPDE1APDE1CIRAK4 | |
| SCHEMBL30283211 | 0.92 | NSD2 (0.41) | CTSKIRAK4LRRK2NSD2ACHE | |
| SCHEMBL24155243 | 0.92 | NSD2 (0.41) | CTSKIRAK4LRRK2NSD2ACHE | |
| SCHEMBL30283042 | 0.91 | ALDH1A1 (0.39) | CTSKPDE1BPDE1APDE1CIRAK4 | |
| SCHEMBL25306447 | 0.78 | JAK2 (0.36) | CTSKPDE1BPDE1APDE1CIRAK4 | |
| SCHEMBL24154957 | 0.78 | JAK2 (0.36) | CTSKPDE1BPDE1APDE1CIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |