Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30320101

COC(=O)Cc1ccc[n+](Cc2ccc(C[N+](C)(C)C)cc2)c1.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ACHE P22303 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
LMNA P02545 3/20 0.33
HDAC3 O15379 4/20 0.32
HDAC4 P56524 4/20 0.32
HDAC1 Q13547 4/20 0.32
HDAC7 Q8WUI4 4/20 0.32
HDAC2 Q92769 4/20 0.32
HDAC10 Q969S8 4/20 0.32
HDAC11 Q96DB2 4/20 0.32
HDAC8 Q9BY41 4/20 0.32
HDAC6 Q9UBN7 4/20 0.32
HDAC9 Q9UKV0 4/20 0.32
HDAC5 Q9UQL6 4/20 0.32
ALDH1A1 P00352 1/20 0.32
CTSG P08311 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30320103 0.85 L3MBTL1 (0.37) L3MBTL1NPSR1ACHELMNAHDAC3
Trifluoroacetic Acid SCHEMBL26087231 0.82 PDK2 (0.37) PDK2L3MBTL1LMNAALDH1A1SMN1; SMN2
Trifluoroacetic Acid SCHEMBL30147380 0.82 CYP4F2 (0.34) PDK2CYP4F2CYP4A11LMNAALDH1A1
Trifluoroacetic Acid SCHEMBL26086337 0.79 ALDH1A1 (0.41) PDK2LMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL26414339 0.79 L3MBTL1 (0.52) L3MBTL1NPSR1CYP4F2CYP4A11LMNA
SCHEMBL26149648 0.78 L3MBTL1 (0.42) L3MBTL1NPSR1ACHELMNAALDH1A1
Trifluoroacetic Acid SCHEMBL21631876 0.78 SYK (0.35) PDK2L3MBTL1NPSR1ACHELMNA
Trifluoroacetic Acid SCHEMBL21632250 0.77 SYK (0.36) PDK2L3MBTL1NPSR1LMNAALDH1A1
Formic Acid SCHEMBL26087463 0.76 NPSR1 (0.47) L3MBTL1NPSR1ACHECYP4F2CYP4A11
Trifluoroacetic Acid SCHEMBL21631878 0.76 CYP11B1 (0.37) PDK2L3MBTL1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4154009-A1 REAGENT FOR MASS SPECTROMETRY F. Hoffmann-La Roche AG (CH) 2023-03-29 EP disclosed