Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22994398 | 1.00 | AURKA (0.51) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL22994484 | 0.91 | BRS3 (0.50) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL25455623 | 0.90 | CCR1 (0.50) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL18729318 | 0.84 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP3A4BRS3KCNH2 | |
| SCHEMBL20781811 | 0.82 | CYP11B1 (0.50) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL12684741 | 0.80 | RAB9A (0.63) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL26316729 | 0.79 | AURKA (0.54) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL26316731 | 0.79 | AURKA (0.54) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL6673316 | 0.79 | AURKA (0.54) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL22788445 | 0.78 | NPC1 (0.48) | AURKAABL1NTRK1LCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974929-A | Organic electroluminescent material and device | 环球展览公司 | 2023-04-18 | — | — | CN | disclosed |