SCHEMBL18729318

SCHEMBL18729318

CC(C)(C)Cc1ccc(-c2ccccc2)nc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 13/20 0.58
CYP11B2 P19099 13/20 0.58
CYP3A4 P08684 1/20 0.55
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
FFAR1 O14842 1/20 0.43
LDHA P00338 1/20 0.43
BRS3 P32247 1/20 0.42
KCNH2 Q12809 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22994484 0.89 BRS3 (0.50) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL18790846 0.88 CYP11B1 (0.50) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL25137959 0.86 CYP11B1 (0.54) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL22994398 0.84 AURKA (0.51) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL30320110 0.84 AURKA (0.51) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL28583022 0.82 CYP11B1 (0.55) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL18790955 0.81 CYP11B1 (0.47) CYP11B1CYP11B2CYP3A4
SCHEMBL20781811 0.80 CYP11B1 (0.50) CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2
SCHEMBL20122190 0.79 CYP11B1 (0.80) CYP11B1CYP11B2CYP3A4NPC1RAB9A
SCHEMBL146559 0.79 NPC1 (0.65) CYP11B1CYP11B2CYP3A4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040512-A Organic electroluminescent material and device thereof 北京夏禾科技有限公司 2025-05-27 CN disclosed
CN-119823187-A Organic electroluminescent material and device thereof 北京夏禾科技有限公司 2025-04-15 CN disclosed
CN-114907413-B Organic electroluminescent material and device thereof 北京夏禾科技有限公司 2025-03-11 CN disclosed
CN-114907412-B Organic electroluminescent material and device thereof 北京夏禾科技有限公司 2025-02-14 CN disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11825734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11139443-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-05 US disclosed
US-20210179564-A1 THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2021-06-17 US disclosed
US-10844084-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-24 US disclosed
US-20200144520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed
US-20190252627-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
US-20190135841-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-05-09 US disclosed
US-20190071404-A1 THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2019-03-07 US disclosed
US-20180175308-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-21 US disclosed
EP-3159350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-04-26 EP disclosed
EP-3001480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2017-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM CYP11B1 3419/4885CYP11B2 2511/4885CYP3A4 2027/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR CYP11B1 3789/4885CYP11B2 3994/4885CYP3A4 3160/4885
US-20200144520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP CYP11B1 1965/4885CYP11B2 1677/4885CYP3A4 523/4885
US-20190071404-A1 THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF JAK2, JAK1, JAK3 CYP11B1 368/4885CYP11B2 295/4885CYP3A4 3142/4885
US-11825734-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP CYP11B1 1965/4885CYP11B2 1677/4885CYP3A4 523/4885
US-20180175308-A1 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP CYP11B1 364/4885CYP11B2 489/4885CYP3A4 334/4885
US-20190252627-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM CYP11B1 1174/4885CYP11B2 1216/4885CYP3A4 784/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 CYP11B1 1221/4885CYP11B2 1004/4885CYP3A4 1083/4885
US-11139443-B2 Organic electroluminescent materials and devices ICOSLG, ORC3, OR10J3 CYP11B1 2255/4885CYP11B2 1775/4885CYP3A4 2415/4885
US-20210179564-A1 THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF JAK2, JAK1, JAK3 CYP11B1 368/4885CYP11B2 295/4885CYP3A4 3142/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 CYP11B1 409/4885CYP11B2 570/4885CYP3A4 1418/4885
US-20190135841-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, YBX3 CYP11B1 1039/4885CYP11B2 958/4885CYP3A4 1527/4885
US-10844084-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, OR10J3 CYP11B1 2755/4885CYP11B2 2038/4885CYP3A4 724/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP CYP11B1 420/4885CYP11B2 444/4885CYP3A4 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.