SCHEMBL30320161

SCHEMBL30320161

Cc1cncc(CCN=[N+]=[N-])n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320160 1.00 CYP2D6 (0.32) CYP2D6HRH1
SCHEMBL24618583 1.00 CYP2D6 (0.32) CYP2D6HRH1
SCHEMBL10834770 0.78 CYP2D6 (0.38) CYP2D6HRH1
SCHEMBL295055 0.72 NOS1 (0.39) CYP2D6HRH1
SCHEMBL30480965 0.72 NOS1 (0.39) CYP2D6HRH1
SCHEMBL5302424 0.71 CYP2D6 (0.35) CYP2D6HRH1
SCHEMBL24618582 0.71 HRH4 (0.36) CYP2D6HRH1
SCHEMBL29792040 0.71 HRH4 (0.36) CYP2D6HRH1
SCHEMBL511339 0.69 NOS2 (0.43) CYP2D6HRH1
SCHEMBL9771908 0.68 HRH1 (0.51) CYP2D6HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867553-A Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists 巴格沃克斯研究有限公司 2023-03-28 CN disclosed