SCHEMBL30320185

SCHEMBL30320185

CS(=O)(=O)N(Cc1ccco1)CC(O)Cn1c2ccccc2c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PER2 O15055 20/20 1.00
CRY1 Q16526 19/20 1.00
CRY2 Q49AN0 19/20 1.00
TSHR P16473 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15380452 1.00 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL29381903 1.00 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL15380660 0.91 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL15380160 0.91 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL15380529 0.90 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL15380157 0.90 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL19825499 0.90 CRY1 (0.80) PER2CRY1CRY2TSHR
SCHEMBL15380810 0.89 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL15380696 0.89 PER2 (1.00) PER2CRY1CRY2TSHR
SCHEMBL15380357 0.87 PER2 (1.00) PER2CRY1CRY2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974763-A Carbazole derivative and application thereof 常州大学 2023-04-18 CN claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
CN-115974763-B Carbazole derivative and application thereof 常州大学 2025-03-11 CN disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
CN-115974763-A Carbazole derivative and application thereof 常州大学 2023-04-18 CN disclosed