Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099638 | 0.97 | PTGS1 (0.48) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL30423808 | 0.97 | PTGS1 (0.48) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL29526628 | 0.93 | PTGS1 (0.48) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL29374494 | 0.92 | PTGS1 (0.48) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL30292792 | 0.91 | PTGS1 (0.52) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL30099519 | 0.91 | GLO1 (0.48) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL29630446 | 0.90 | PTGS1 (0.47) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL14774754 | 0.88 | PTGS1 (0.50) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL22111140 | 0.88 | PTGS1 (0.53) | PTGS1GSTK1GRM8GRM6GRIN2D | |
| SCHEMBL30658618 | 0.88 | FOLH1 (0.49) | PTGS1GSTK1GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795454-B2 | Targeted delivery system | CEDARS-SINAI MEDICAL CENTER (US) | 2023-10-24 | — | — | US | disclosed |
| CN-115975057-A | Solid-phase synthesis method of clodotoxin | 杭州信海医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |