Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 3/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.54 |
| ▸ | PRKDC | P78527 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | HCK | P08631 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | ROS1 | P08922 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096485 | 1.00 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL18250087 | 0.85 | DYRK3 (0.47) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL21028946 | 0.83 | PIK3CD (0.55) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL868744 | 0.80 | PIK3CD (0.51) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL16864520 | 0.78 | PIK3CD (0.54) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL16701523 | 0.78 | ADK (0.49) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL23063891 | 0.78 | SRC (0.46) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL4572201 | 0.77 | RET (0.48) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL868521 | 0.77 | DYRK3 (0.51) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL19283009 | 0.76 | ADK (0.49) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075513-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-05-05 | — | — | CN | disclosed |