Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 12/20 | 0.67 |
| ▸ | MT-CO1 | P00395 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357628 | 0.82 | CCKAR (0.68) | CCKARMT-CO1CNR2 | |
| SCHEMBL502229 | 0.80 | CCKAR (1.00) | CCKARMT-CO1CNR2 | |
| SCHEMBL12477368 | 0.75 | CCKAR (0.68) | CCKAR | |
| SCHEMBL3137597 | 0.74 | CCKAR (0.66) | CCKARMT-CO1CNR2 | |
| SCHEMBL2152210 | 0.73 | CCKAR (1.00) | CCKARMT-CO1CNR2 | |
| SCHEMBL2152958 | 0.72 | CCKAR (0.84) | CCKAR | |
| SCHEMBL2913085 | 0.71 | CCKAR (0.79) | CCKARMT-CO1CNR2 | |
| SCHEMBL2657553 | 0.71 | CCKAR (0.67) | CCKARMT-CO1CNR2 | |
| SCHEMBL12510286 | 0.70 | CCKAR (0.83) | CCKAR | |
| SCHEMBL2913088 | 0.69 | CCKAR (0.75) | CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924343-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | Merck Sharp & Dohme Corp. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2010036613-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |