Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 16/20 | 0.66 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657553 | 0.94 | CCKAR (0.67) | CCKARMT-CO1CNR2 | |
| SCHEMBL2357628 | 0.92 | CCKAR (0.68) | CCKARMT-CO1CNR2 | |
| SCHEMBL3612093 | 0.89 | CCKAR (0.63) | CCKAR | |
| SCHEMBL12477368 | 0.87 | CCKAR (0.68) | CCKAR | |
| SCHEMBL3980545 | 0.83 | CCKAR (0.65) | CCKAR | |
| SCHEMBL3881950 | 0.82 | CCKAR (0.52) | CCKARMT-CO1CNR2 | |
| SCHEMBL502712 | 0.80 | CCKAR (1.00) | CCKAR | |
| SCHEMBL502707 | 0.76 | CCKAR (1.00) | CCKAR | |
| SCHEMBL2152386 | 0.74 | CCKAR (0.92) | CCKAR | |
| SCHEMBL502739 | 0.74 | CCKAR (1.00) | CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010179-B1 | SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-07-07 | — | — | EP | disclosed |