Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 13/20 | 0.83 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17551781 | 1.00 | SGMS2 (0.83) | SGMS2LRRK2POLBTAAR1 | |
| SCHEMBL30322947 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2POLBTAAR1 | |
| SCHEMBL17551870 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2POLBTAAR1 | |
| SCHEMBL19133749 | 0.91 | SGMS2 (1.00) | SGMS2LRRK2 | |
| SCHEMBL30322841 | 0.91 | SGMS2 (1.00) | SGMS2LRRK2 | |
| SCHEMBL17551782 | 0.89 | SGMS2 (0.79) | SGMS2LRRK2 | |
| SCHEMBL30322886 | 0.89 | SGMS2 (0.79) | SGMS2LRRK2 | |
| SCHEMBL17551772 | 0.89 | SGMS2 (0.83) | SGMS2LRRK2POLBTAAR1 | |
| SCHEMBL17551776 | 0.88 | SGMS2 (0.78) | SGMS2LRRK2 | |
| SCHEMBL30322760 | 0.88 | SGMS2 (0.78) | SGMS2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196191-B1 | 2-ALKYLOXY BENZENE FORMYL ARYLAMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2023-04-19 | — | — | EP | disclosed |