Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 11/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30322841 | 1.00 | SGMS2 (1.00) | SGMS2LRRK2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL17551873 | 0.94 | SGMS2 (0.89) | SGMS2LRRK2 | |
| SCHEMBL17551817 | 0.92 | SGMS2 (0.85) | SGMS2LRRK2 | |
| SCHEMBL31261706 | 0.91 | SGMS2 (0.84) | SGMS2LRRK2 | |
| SCHEMBL31261673 | 0.91 | SGMS2 (0.84) | SGMS2LRRK2 | |
| SCHEMBL17551870 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2 | |
| SCHEMBL30322883 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2 | |
| SCHEMBL17551781 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2 | |
| SCHEMBL30322947 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2 | |
| SCHEMBL17551772 | 0.91 | SGMS2 (0.83) | SGMS2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196191-B1 | 2-ALKYLOXY BENZENE FORMYL ARYLAMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2023-04-19 | — | — | EP | disclosed |
| EP-3196191-B1 | 2-ALKYLOXY BENZENE FORMYL ARYLAMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2023-04-19 | — | — | EP | disclosed |
| US-10196359-B2 | 2-alkyloxy benzene formyl arylamine compound and pharmaceutical use thereof | FUDAN UNIVERSITY (CN) | 2019-02-05 | — | — | US | disclosed |
| CN-105348182-B | 2 alkoxy benzene formyl arylamine class compounds and its medicinal usage | 复旦大学 | 2018-04-13 | — | — | CN | disclosed |
| US-20170253564-A1 | 2-Alkyloxy benzene formyl arylamine compound and pharmaceutical use thereof | FUDAN UNIVERSITY (CN) | 2017-09-07 | — | — | US | disclosed |
| EP-3196191-A1 | 2-ALKYLOXY BENZENE FORMYL ARYLAMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Fudan University (CN) | 2017-07-26 | — | — | EP | disclosed |
| CN-105348182-A | 2-alkoxyl benzoyl arylamine compound and pharmaceutical use thereof | UNIV FUDAN | 2016-02-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253564-A1 | 2-Alkyloxy benzene formyl arylamine compound and pharmaceutical use thereof | SMS, SGMS2, SGMS1 | SGMS2 2/4885LRRK2 3581/4885ALDH1A1 2213/4885 |
| US-10196359-B2 | 2-alkyloxy benzene formyl arylamine compound and pharmaceutical use thereof | SMS, SGMS2, SGMS1 | SGMS2 2/4885LRRK2 3581/4885ALDH1A1 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.