Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 8/20 | 0.37 |
| ▸ | JAK1 | P23458 | 8/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323335 | 0.87 | JAK2 (0.37) | BRD4CREBBPJAK2JAK1TYK2 | |
| SCHEMBL23388918 | 0.78 | TLR7 (0.41) | JAK2JAK1TYK2JAK3DHODH | |
| SCHEMBL23423434 | 0.77 | LMNA (0.46) | JAK2JAK1TYK2JAK3DHODH | |
| SCHEMBL30323328 | 0.76 | BRD4 (0.45) | BRD4CREBBPJAK2JAK1TYK2 | |
| SCHEMBL30323407 | 0.76 | JAK2 (0.37) | JAK2JAK1TYK2JAK3CCR5 | |
| SCHEMBL30323327 | 0.75 | JAK2 (0.38) | BRD4CREBBPJAK2JAK1TYK2 | |
| SCHEMBL30323467 | 0.74 | BRD4 (0.45) | BRD4CREBBPJAK2JAK1DHODH | |
| SCHEMBL22571385 | 0.74 | RXFP1 (0.43) | JAK2JAK1TYK2JAK3EPHX2 | |
| SCHEMBL23423242 | 0.74 | LMNA (0.45) | JAK2JAK1TYK2JAK3DHODH | |
| SCHEMBL30323356 | 0.73 | TLR7 (0.43) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049199-A1 | AZOLE COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2023-03-30 | — | — | WO | disclosed |