SCHEMBL30323863

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	NTSR1	P30989	17/20	0.63

▸	NTSR2	O95665	16/20	0.63

▸	SORT1	Q99523	15/20	0.63

▸	OPRM1	P35372	1/20	0.59

▸	OPRD1	P41143	1/20	0.59

▸	F2	P00734	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29860120	0.90	F2 (0.64)	NTSR1NTSR2SORT1OPRD1F2
SCHEMBL30921554	0.89	SLC6A2 (0.67)	NTSR1NTSR2SORT1
SCHEMBL2039240	0.88	NTSR1 (0.68)	NTSR1NTSR2SORT1
SCHEMBL29967012	0.88	NTSR1 (0.68)	NTSR1NTSR2SORT1
SCHEMBL29860392	0.88	NTSR1 (0.64)	NTSR1NTSR2SORT1
SCHEMBL30637760	0.88	NTSR1 (0.64)	NTSR1NTSR2SORT1
SCHEMBL24195742	0.88	F2 (0.65)	NTSR1NTSR2OPRD1F2
SCHEMBL31084238	0.87	F2 (0.62)	NTSR1NTSR2SORT1F2
SCHEMBL31656330	0.86	OPRD1 (0.61)	NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL30753221	0.85	NMUR2 (0.61)	NTSR1NTSR2OPRD1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114014909-B	Polypeptide, application thereof and pharmaceutical composition	无锡市儿童医院	2023-05-16	—	—	CN	disclosed