Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379295 | 0.88 | MAPT (0.57) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3379886 | 0.88 | LMNA (0.59) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3380826 | 0.85 | LMNA (0.60) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2186493 | 0.85 | ALDH1A1 (0.62) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL303248 | 0.84 | LMNA (0.59) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3376241 | 0.84 | LMNA (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3379800 | 0.83 | LMNA (0.58) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL302132 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3379037 | 0.82 | MAPT (0.57) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3377290 | 0.82 | LMNA (0.57) | LMNAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500836-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2342177-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-07-13 | — | — | EP | claimed |
| WO-2010023448-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |