SCHEMBL30325218

SCHEMBL30325218

O=C1CC(c2ccccc2I)C(=O)N1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 18/20 0.61
LMNA P02545 1/20 0.58
CYP19A1 P11511 1/20 0.46
CYP2C19 P33261 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
DDB1 Q16531 1/20 0.45
CRBN Q96SW2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6918058 0.79 IDO1 (0.61) IDO1LMNACYP19A1CYP2C19ABCG2
SCHEMBL2529914 0.79 DDB1 (0.71) IDO1LMNACYP19A1DDB1CRBN
SCHEMBL9818019 0.79 IDO1 (0.61) IDO1LMNACYP19A1CYP2C19ABCG2
SCHEMBL28972311 0.79 IDO1 (0.61) IDO1LMNACYP2C19ABCG2
SCHEMBL5323542 0.79 IDO1 (0.61) IDO1LMNA
SCHEMBL9387969 0.76 IDO1 (1.00) IDO1LMNACYP19A1DDB1CRBN
Bromide SCHEMBL28839335 0.75 IDO1 (0.97) IDO1LMNADDB1CRBN
SCHEMBL29011873 0.75 IDO1 (0.60) IDO1LMNACYP19A1CYP2C19ABCG2
SCHEMBL15359680 0.75 HSD17B10 (0.62) IDO1LMNA
SCHEMBL45434 0.73 IDO1 (1.00) IDO1LMNACYP2C19ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115581847-A Photodynamic balloon catheter system 杭州矩正医疗科技有限公司 2023-01-10 CN disclosed