Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28155131 | 0.91 | IDO1 (0.52) | IDO1LMNACYP19A1DDB1CRBN | |
| SCHEMBL6275913 | 0.80 | BRD4 (0.44) | IDO1LMNAALDH1A1CYP2C19 | |
| SCHEMBL6918058 | 0.79 | IDO1 (0.61) | IDO1LMNACYP19A1DDB1CRBN | |
| SCHEMBL30325218 | 0.79 | IDO1 (0.61) | IDO1LMNACYP19A1DDB1CRBN | |
| SCHEMBL5323542 | 0.79 | IDO1 (0.61) | IDO1LMNAALDH1A1 | |
| SCHEMBL2529914 | 0.79 | DDB1 (0.71) | IDO1LMNACYP19A1DDB1CRBN | |
| SCHEMBL28972311 | 0.79 | IDO1 (0.61) | IDO1LMNAALDH1A1CYP2C19ABCG2 | |
| SCHEMBL18648917 | 0.77 | LMNA (0.46) | LMNAALDH1A1 | |
| SCHEMBL9387969 | 0.76 | IDO1 (1.00) | IDO1LMNACYP19A1DDB1CRBN | |
| Bromide SCHEMBL28839335 | 0.75 | IDO1 (0.97) | IDO1LMNADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302643-B1 | LACTONE-MODIFIED MANNICH BASE DISPERSANT ADDITIVES USEFUL IN OLEAGINOUS COMPOSITIONS | EXXON CHEMICAL PATENTS INC. (US) | 1991-11-21 | — | — | EP | disclosed |