Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75642 | 0.89 | MAPT (0.41) | MAPTGAAPKMHTTMCL1 | |
| SCHEMBL28296896 | 0.82 | CHRM1 (0.43) | MAPTGAAHTTALDH1A1GABRA1 | |
| SCHEMBL30327071 | 0.82 | ALDH1A1 (0.45) | MAPTGAAALDH1A1KDM4EGABRA1 | |
| SCHEMBL376187 | 0.81 | ALDH1A1 (0.40) | MAPTGAAPKMHTTMCL1 | |
| SCHEMBL11331423 | 0.80 | APP (0.41) | MAPTGAAPKMHTTMCL1 | |
| SCHEMBL4314898 | 0.80 | MAPT (0.36) | MAPTGAAPKMHTTMCL1 | |
| SCHEMBL19886263 | 0.80 | MAPT (0.44) | MAPTGAAPKMHTTMCL1 | |
| SCHEMBL5921994 | 0.80 | SLC2A1 (0.47) | MAPTGAAPKMHTTMCL1 | |
| SCHEMBL11672106 | 0.79 | ALDH1A1 (0.43) | MAPTGAAALDH1A1KDM4ETYR | |
| SCHEMBL13649911 | 0.78 | SLC2A1 (0.46) | MAPTGAAALDH1A1KDM4EGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484420-B | Method for synthesizing triarylmethane derivative and triarylmethane derivative obtained by same | 天津师范大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-111484419-B | Method for synthesizing triarylmethane derivative | 天津师范大学 | 2023-03-31 | — | — | CN | disclosed |