SCHEMBL75642

SCHEMBL75642

Cc1cc(N(C)C)ccc1C(c1ccccc1)c1ccc(N(C)C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
GAA P10253 2/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 1/20 0.39
SLC2A1 P11166 1/20 0.37
PSMB5 P28074 1/20 0.36
TSHR P16473 4/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
RELA Q04206 1/20 0.36
ADK P55263 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
ALOX15 P16050 1/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
RAB9A P51151 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL376187 0.91 ALDH1A1 (0.40) MAPTGAAPKMHTTMCL1
SCHEMBL19886263 0.89 MAPT (0.44) MAPTGAAPKMHTTMCL1
SCHEMBL4314898 0.89 MAPT (0.36) MAPTGAAPKMHTTMCL1
SCHEMBL30327005 0.89 MAPT (0.41) MAPTGAAPKMHTTMCL1
SCHEMBL5921994 0.89 SLC2A1 (0.47) MAPTGAAPKMHTTMCL1
SCHEMBL5007878 0.86 ALDH1A1 (0.39) MAPTGAAALDH1A1KDM4ESLC2A1
SCHEMBL5009553 0.85 SLC2A1 (0.47) MAPTGAAPKMHTTMCL1
SCHEMBL3193700 0.85 MAPT (0.46) MAPTGAAPKMHTTMCL1
SCHEMBL38662618 0.85 MAPT (0.46) MAPTGAAPKMHTTMCL1
SCHEMBL4855293 0.84 RELA (0.45) MAPTGAAHTTALDH1A1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1951 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859656-B1 ORGANOMETALLIC COMPLEXES DU PONT (US) 2013-07-17 EP claimed
US-8362463-B2 Organometallic complexes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-01-29 US claimed
US-20090206327-A1 ORGANOMETALLIC COMPLEXES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-20 US claimed
EP-1859656-A2 ORGANOMETALLIC COMPLEXES E.I. du Pont de Nemours and Company (US) 2007-11-28 EP claimed
EP-1793435-A2 Organic light emitting device Samsung SDI Co., Ltd. (KR) 2007-06-06 EP claimed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US claimed
WO-2006072002-A2 ORGANOMETALLIC COMPLEXES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-07-06 WO claimed
US-20060021647-A1 Molecular photovoltaics, method of manufacture and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. 2006-02-02 US claimed
US-6967062-B2 White light-emitting OLED device having a blue light-emitting layer doped with an electron-transporting or a hole-transporting material or both EASTMAN KODAK COMPANY (US) 2005-11-22 US claimed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US claimed
US-20040185300-A1 White light-emitting OLED device having a blue light-emitting layer doped with an electron-transporting or a hole-transporting material or both EASTMAN KODAK COMPANY 2004-09-23 US claimed
EP-0120673-B1 ORGANIC ELECTROLUMINESCENT DEVICES HAVING IMPROVED POWER CONVERSION EFFICIENCIES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-01 EP claimed
US-4539507-A CHARGE TRANSFER COMPOUNDS EASTMAN KODAK COMPANY (US) 1985-09-03 US claimed
EP-0120673-A2 Organic electroluminescent devices having improved power conversion efficiencies EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-6423429-B1 None US disclosed
JP-60118845-A None JP disclosed
JP-60194460-A None JP disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090206327-A1 ORGANOMETALLIC COMPLEXES SLC25A11, TIMM9, TIMM50 MAPT 2002/4885GAA 3750/4885PKM 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.