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SCHEMBL30327447

SCHEMBL30327447

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(C)C)[C@@H](C)O)C(C)C

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 1/20 0.64
▸ CALCR P30988 1/20 0.64
▸ TFPI P10646 4/20 0.63
▸ NMUR2 Q9GZQ4 3/20 0.61
▸ NMUR1 Q9HB89 3/20 0.61
▸ NPY2R P49146 7/20 0.61
▸ NPY4R P50391 7/20 0.61
▸ NPY5R Q15761 7/20 0.61
▸ NPY1R P25929 5/20 0.61
▸ EP300 Q09472 1/20 0.61
▸ HIF1A Q16665 1/20 0.61
▸ KDM1A O60341 1/20 0.59
▸ IL23R Q5VWK5 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32670346 0.95 RAMP3 (0.64) RAMP3CALCRTFPINMUR2NMUR1
SCHEMBL31182847 0.95 TFPI (0.62) RAMP3CALCRTFPINMUR2NMUR1
SCHEMBL9717732 0.91 NPY2R (0.68) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL31182462 0.91 CALCR (0.64) RAMP3CALCRTFPINMUR2NMUR1
SCHEMBL31182617 0.90 NPY2R (0.61) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30485544 0.90 NMUR2 (0.59) RAMP3CALCRTFPINMUR2NMUR1
SCHEMBL30607401 0.90 NMUR2 (0.65) RAMP3CALCRTFPINMUR2NMUR1
SCHEMBL31182566 0.90 TFPI (0.68) CALCRTFPINPY2RNPY4RNPY5R
SCHEMBL31707403 0.89 CXCR4 (0.62) RAMP3CALCRTFPINMUR2NMUR1
SCHEMBL30435007 0.89 NPY2R (0.67) RAMP3CALCRTFPINMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12447198-B2 Peptides and fragments for treating diabetes and associated metabolic diseases BETAVIVE LTD. (IL) 2025-10-21 — — US disclosed
EP-4415744-A1 PEPTIDES AND FRAGMENTS FOR TREATING DIABETES AND ASSOCIATED METABOLIC DISEASES Betavive Ltd. (IL) 2024-08-21 — — EP disclosed
CN-118369109-A Peptides and fragments for the treatment of diabetes and related metabolic disorders 贝塔维有限公司 2024-07-19 — — CN disclosed
US-20230120635-A1 Peptides and Fragments for Treating Diabetes and Associated Metabolic Diseases BETAVIVE LTD. (IL) 2023-04-20 — — US disclosed
WO-2023062545-A1 PEPTIDES AND FRAGMENTS FOR TREATING DIABETES AND ASSOCIATED METABOLIC DISEASES BETAVIVE LTD. (IL) 2023-04-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230120635-A1 Peptides and Fragments for Treating Diabetes and Associated Metabolic Diseases IAPP, IGFBP2, IGFBP1 RAMP3 2356/4885CALCR 621/4885TFPI 1143/4885
US-12447198-B2 Peptides and fragments for treating diabetes and associated metabolic diseases IAPP, IGFBP2, IGFBP1 RAMP3 2356/4885CALCR 621/4885TFPI 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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