Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 6/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327616 | 0.84 | CYP11B2 (0.46) | CYP11B2ACACBGPR119SCD5HDAC2 | |
| SCHEMBL30328998 | 0.84 | CYP11B2 (0.46) | CYP11B2ACACBGPR119SCD5HDAC2 | |
| SCHEMBL20469052 | 0.81 | CYP11B2 (0.51) | CYP11B2ACACBGPR119SCD5 | |
| SCHEMBL30327758 | 0.81 | CYP11B2 (0.45) | CYP11B2ACACBSCD5HDAC2RORC | |
| SCHEMBL30328270 | 0.78 | GPR119 (0.46) | CYP11B2ACACBGPR119SCD5HDAC2 | |
| SCHEMBL30328622 | 0.76 | GPR119 (0.46) | CYP11B2ACACBGPR119SCD5HDAC2 | |
| SCHEMBL20468832 | 0.76 | CYP11B2 (0.52) | CYP11B2ACACBGPR119SCD5HDAC2 | |
| SCHEMBL30327779 | 0.76 | CYP11B2 (0.46) | CYP11B2ACACBSCD5HDAC2RORC | |
| SCHEMBL20468958 | 0.76 | CYP11B2 (0.48) | CYP11B2ACACBGPR119SCD5EIF2AK4 | |
| SCHEMBL20898976 | 0.75 | GPR119 (0.46) | CYP11B2ACACBGPR119SCD5EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |