Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329202 | 0.90 | CYP11B2 (0.48) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL30327800 | 0.89 | CYP11B2 (0.48) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL30329274 | 0.82 | CYP11B2 (0.45) | CYP11B2ACACBEIF2AK4RETPOLB | |
| SCHEMBL25164359 | 0.82 | CYP11B2 (0.47) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL30329263 | 0.81 | CYP11B2 (0.48) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL30328050 | 0.81 | CYP11B2 (0.55) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL25164474 | 0.81 | CYP11B2 (0.55) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL30327857 | 0.81 | CYP11B2 (0.48) | CYP11B2CKS1BSKP1SKP2ACACB | |
| SCHEMBL30328034 | 0.81 | CYP11B2 (0.43) | CYP11B2ACACBEIF2AK4RETPOLB | |
| SCHEMBL30328179 | 0.80 | CYP11B2 (0.47) | CYP11B2CKS1BSKP1SKP2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |