Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 7/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25163776 | 0.92 | LIPE (0.38) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL30327911 | 0.92 | LIPE (0.38) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL30329455 | 0.90 | LIPE (0.38) | LIPEEBPHCRTR2HCRTR1ADORA3 | |
| SCHEMBL25163530 | 0.90 | LIPE (0.38) | LIPEEBPHCRTR2HCRTR1ADORA3 | |
| SCHEMBL30327945 | 0.86 | HCRTR2 (0.38) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL25164789 | 0.86 | HCRTR2 (0.38) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL25164004 | 0.81 | LIPE (0.35) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL30327665 | 0.81 | LIPE (0.35) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL25163924 | 0.79 | DHFR (0.37) | LIPEEBPHCRTR2HCRTR1EGLN1 | |
| SCHEMBL30329366 | 0.79 | DHFR (0.37) | LIPEEBPHCRTR2HCRTR1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |