Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 5/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30328510 | 0.81 | SMN1; SMN2 (0.53) | CYP11B2RETMEN1MAPTKMT2A | |
| SCHEMBL14614610 | 0.81 | CKS1B (0.59) | RETMEN1MAPTTSHRKMT2A | |
| SCHEMBL20468949 | 0.81 | CYP11B2 (0.53) | CYP11B2ACACBSCD5RETMEN1 | |
| SCHEMBL20468957 | 0.81 | ACACB (0.52) | CYP11B2ACACBSCD5RETTSHR | |
| SCHEMBL30912263 | 0.80 | RET (0.46) | CYP11B2ACACBRETTSHRGPR119 | |
| SCHEMBL17925041 | 0.80 | GPR119 (0.52) | CYP11B2ACACBRETGPR119ALDH1A1 | |
| SCHEMBL20468943 | 0.80 | CYP11B2 (0.53) | CYP11B2ACACBSCD5RETTSHR | |
| SCHEMBL20468832 | 0.80 | CYP11B2 (0.52) | CYP11B2ACACBSCD5GPR119SPR | |
| SCHEMBL20469138 | 0.79 | GPR119 (0.60) | CYP11B2ACACBSCD5RETTSHR | |
| SCHEMBL23108168 | 0.79 | GPR119 (0.58) | CYP11B2SCD5MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |