Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30328885 | 0.99 | PIM1 (0.41) | PIM1PHGDHPIM3PIM2CYP2D6 | |
| SCHEMBL30328097 | 0.86 | PHGDH (0.39) | PIM1PHGDHPIM3PIM2CYP2D6 | |
| Hydrochloric Acid SCHEMBL30329091 | 0.85 | PHGDH (0.38) | PIM1PHGDHPIM3PIM2TSHR | |
| SCHEMBL2254829 | 0.81 | ADRB2 (0.51) | PHGDHALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL30327874 | 0.80 | PIM1 (0.42) | PIM1PIM3PIM2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL30327990 | 0.79 | PIM1 (0.41) | PIM1PIM3PIM2CYP2D6CYP3A4 | |
| SCHEMBL30328622 | 0.78 | GPR119 (0.46) | PHGDHALDH1A1FFAR4MEN1KMT2A | |
| SCHEMBL30328479 | 0.77 | FFAR4 (0.37) | PHGDHALDH1A1ADRB2LCATFFAR4 | |
| Hydrochloric Acid SCHEMBL30328032 | 0.76 | PIM1 (0.40) | PIM1PIM3PIM2CYP2D6CYP3A4 | |
| SCHEMBL20469193 | 0.75 | OGA (0.47) | PIM1PIM3PIM2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |