Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 8/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.38 |
| ▸ | SKP1 | P63208 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30328257 | 0.95 | CYP11B2 (0.42) | CYP11B2EIF2AK4RETCKS1BSKP1 | |
| SCHEMBL30328854 | 0.91 | RET (0.42) | CYP11B2EIF2AK4RETCKS1BSKP1 | |
| SCHEMBL30329127 | 0.86 | GRIN2B (0.38) | JAK3GRIN2B | |
| SCHEMBL25163744 | 0.85 | CYP11B2 (0.41) | CYP11B2EIF2AK4RETACACBPIK3CA | |
| SCHEMBL25163743 | 0.84 | CYP11B2 (0.40) | CYP11B2EIF2AK4RETACACBPIK3CA | |
| SCHEMBL25163962 | 0.81 | GRIN2B (0.38) | JAK3GRIN2B | |
| SCHEMBL30328836 | 0.81 | GRIN2B (0.38) | JAK3GRIN2B | |
| SCHEMBL25164246 | 0.81 | CYP3A4 (0.49) | — | |
| SCHEMBL30329504 | 0.81 | CYP3A4 (0.49) | — | |
| SCHEMBL25163849 | 0.81 | VNN1 (0.42) | JAK3GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |