SCHEMBL303313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13065011	0.93	LMNA (0.55)	LMNAKMT2AHPGDALDH1A1CA12
	SCHEMBL303740	0.90	LMNA (0.47)	LMNAKMT2AHPGDALDH1A1CA12
	SCHEMBL3377977	0.89	LMNA (0.52)	LMNAKMT2AHPGDALDH1A1PKM
	SCHEMBL302061	0.89	LMNA (0.54)	LMNAKMT2AHPGDALDH1A1CA12
	SCHEMBL3377438	0.85	LMNA (0.54)	LMNAKMT2AHPGDALDH1A1PKM
	SCHEMBL3377152	0.85	LMNA (0.60)	LMNAKMT2AHPGDALDH1A1PKM
	SCHEMBL2211106	0.84	LMNA (0.48)	LMNAKMT2AHPGDALDH1A1CA12
	SCHEMBL3376238	0.84	LMNA (0.50)	LMNAKMT2AHPGDALDH1A1PKM
	SCHEMBL13065009	0.81	LMNA (0.50)	LMNAKMT2AHPGDALDH1A1PKM
	SCHEMBL17075498	0.81	LMNA (0.45)	LMNAKMT2AHPGDALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.