Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30332259 | 0.82 | JAK2 (0.45) | PDK2CREBBPMET | |
| SCHEMBL23753798 | 0.78 | CNR1 (0.52) | PDK2ESR2GABRG2GABRB3GABRA5 | |
| SCHEMBL15936754 | 0.77 | PDK2 (0.53) | PDK2CREBBPFEN1PDK1PDK3 | |
| SCHEMBL11826508 | 0.76 | L3MBTL1 (0.61) | PDK2FEN1PDK1PDK3NAMPT | |
| SCHEMBL30332368 | 0.75 | DPP4 (0.51) | PDK2FEN1PDK1PDK3NAMPT | |
| SCHEMBL31590468 | 0.74 | KIT (0.48) | PDK2CREBBPNAMPTMET | |
| SCHEMBL31009657 | 0.73 | ALDH1A1 (0.39) | PDK2CREBBPFEN1IRAK4 | |
| SCHEMBL31009656 | 0.73 | ALDH1A1 (0.39) | PDK2CREBBPFEN1IRAK4 | |
| SCHEMBL31130932 | 0.73 | RET (0.42) | PDK2 | |
| SCHEMBL30332210 | 0.72 | PDK2 (0.48) | PDK2ESR2CREBBPCYP19A1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046128-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-30 | — | — | WO | disclosed |