Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30332214 | 0.84 | PDE9A (0.41) | NCF1P2RX7PDE9AF2F10 | |
| SCHEMBL20282340 | 0.78 | GRM4 (0.43) | HCRTR1HCRTR2RXRAGRIN1GRIN2B | |
| SCHEMBL30332311 | 0.77 | CYP1A2 (0.46) | NCF1RXRAGRIN1GRIN2B | |
| SCHEMBL30332120 | 0.74 | CREBBP (0.40) | HCRTR1HCRTR2KCNJ5CREBBP | |
| SCHEMBL15238099 | 0.74 | PNMT (0.41) | NCF1P2RX7CREBBPBPTFKAT2B | |
| SCHEMBL30607719 | 0.74 | NCF1 (0.36) | NCF1 | |
| SCHEMBL30607609 | 0.74 | NCF1 (0.36) | NCF1P2RX7CREBBPBPTFKAT2B | |
| SCHEMBL15941059 | 0.73 | GAA (0.55) | CYP11B1CYP11B2 | |
| SCHEMBL30332384 | 0.72 | HCRTR1 (0.35) | HCRTR1HCRTR2NCF1F2F10 | |
| SCHEMBL21486445 | 0.72 | HCRTR1 (0.35) | HCRTR1HCRTR2NCF1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046128-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-30 | — | — | WO | disclosed |